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Literature summary for 3.4.22.15 extracted from

  • Day, S.R.; Dalton, J.P.; Clough, K.A.; Leonardo, L.; Tiu, W.U.; Brindley, P.J.
    Characterization and cloning of the cathepsin L proteinase of Schistosoma japonicum (1995), Biochem. Biophys. Res. Commun., 217, 1-9.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
-
Schistosoma japonicum

Inhibitors

Inhibitors Comment Organism Structure
benzyloxycarbonyl-Phe-Ala-CNH2
-
Schistosoma japonicum
Benzyloxycarbonyl-Phe-Phe-CHN2
-
Schistosoma japonicum
trans-epoxysuccinyl-L-leucylamido-(4-guanidino)butane
-
Schistosoma japonicum

Organism

Organism UniProt Comment Textmining
Schistosoma japonicum
-
cathepsin L1 and L2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide + H2O
-
Schistosoma japonicum ?
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.2
-
hydrolysis of benzyloxycarbonyl-Phe-Arg-4-methylcoumarin 7-amide Schistosoma japonicum