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Literature summary for 3.4.22.15 extracted from
- Rat mammary gland in culture secretes a stable high molecular weight form of cathepsin L (1985), Biochem. Biophys. Res. Commun., 131, 402-407.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| benzyloxycarbonyl-Phe-Ala-CNH2 | - |
Rattus norvegicus |  |
| Benzyloxycarbonyl-Phe-Phe-CHN2 | - |
Rattus norvegicus | |
| leupeptin | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| additional information | the enzyme is secreted from mammary gland | Rattus norvegicus | - |
- |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 35000 | - |
gel filtration | Rattus norvegicus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| mammary gland | - |
Rattus norvegicus | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C, pH 7.0, 50% loss of activity after 1 month | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| azocasein + H2O | - |
Rattus norvegicus | ? | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5 | 5.5 | hydrolysis of azocasein | Rattus norvegicus |
pH Stability
| pH Stability | pH Stability Maximum | Comment | Organism |
|---|---|---|---|
| 7.2 | 7.4 | 37°C, stable | Rattus norvegicus |
| 8 | - |
40°C, 60 min, stable | Rattus norvegicus |
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Release 2023.1 (January 2023)
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