BRENDA - Reference to 3.4.22.10; Id = 733964

additional information

Streptococcus pyogenes

SpeB has no immunoglobulin-degrading activity in human plasma or blood

?

-

Streptococcus pyogenes

-

IgA + H2O

efficiently cleaved under reducing conditions but not under nonreducing conditions

733964

Streptococcus pyogenes

?

-

?

IgG + H2O

efficiently cleaved under reducing conditions but not under nonreducing conditions

733964

Streptococcus pyogenes

?

-

?

IgM + H2O

efficiently cleaved under reducing conditions but not under nonreducing conditions

733964

Streptococcus pyogenes

?

-

?

additional information

SpeB has no immunoglobulin-degrading activity in human plasma or blood

733964

Streptococcus pyogenes

?

-

37

-

assay at

Streptococcus pyogenes

additional information

Streptococcus pyogenes

SpeB has no immunoglobulin-degrading activity in human plasma or blood

?

-

IgA + H2O

efficiently cleaved under reducing conditions but not under nonreducing conditions

733964

Streptococcus pyogenes

?

-

?

IgG + H2O

efficiently cleaved under reducing conditions but not under nonreducing conditions

733964

Streptococcus pyogenes

?

-

?

IgM + H2O

efficiently cleaved under reducing conditions but not under nonreducing conditions

733964

Streptococcus pyogenes

?

-

?

additional information

SpeB has no immunoglobulin-degrading activity in human plasma or blood

733964

Streptococcus pyogenes

?

-

37

-

assay at

Streptococcus pyogenes

733967

Chella Krishnan

Metal-mediated modulation of s ...

Streptococcus pyogenes

Infect. Immun.

82

2992-3001

2014

-

1

-

3

-

2

1

-

5

-

1

-

1

-

1

-

1

-

1

3

-

2

1

-

1

-

1

-

733964

Persson

The streptococcal cysteine pro ...

Streptococcus pyogenes

Infect. Immun.

81

2236-2241

2013

-

1

-

4

-

4

-

1

-

1

-

4

-

1

-

734212

Sumitomo

Group A streptococcal cysteine ...

Streptococcus pyogenes

J. Biol. Chem.

288

13317-13324

2013

-

4

-

1

-

3

-

1

-

1

-

1

-

3

-

1

-

1

-

1

-

734185

Gonzalez-Paez

Ultrahigh and high resolution ...

Streptococcus pyogenes, Streptococcus pyogenes ATCC 10782

J. Biol. Chem.

287

24412-24426

2012

-

1

9

-

2

10

-

2

-

2

-

1

-

10

1

-

1

9

-

2

-

10

-

2

-

1

-

10

1

-

7

717218

Meinert Niclasen

Streptococcal pyogenic exotoxi ...

Streptococcus pyogenes, Streptococcus pyogenes Alab49, Streptococcus pyogenes AP1

Biochem. J.

434

123-132

2011

-

1

-

3

-

8

-

1

-

3

-

1

-

3

-

1

-

3

-

1

-

717311

Nelson

Cysteine proteinase SpeB from ...

Streptococcus pyogenes

Biol. Chem.

392

1077-1088

2011

-

2

31

-

1

-

31

1

-

2

31

-

31

1

-

718299

Connolly

Srv mediated dispersal of stre ...

Streptococcus sp., Streptococcus sp. MGAS315, Streptococcus sp. RGAS053

PLoS ONE

6

e28640

2011

-

1

-

1

-

3

-

1

-

1

-

1

-

1

-

1

-

718127

Kurupati

Chemokine-cleaving Streptococc ...

Streptococcus pyogenes, Streptococcus pyogenes H292

Mol. Microbiol.

76

1387-1397

2010

-

1

11

-

2

-

11

-

1

11

-

11

-

1

-

698880

Wang

Solution structure and backbon ...

Streptococcus pyogenes

J. Biol. Chem.

284

10957-10967

2009

-

1

-

9

-

2

-

2

-

3

-

1

-

2

-

3

-

1

-

1

-

9

-

2

-

2

-

1

-

2

-

3

-

1

-

707720

Berggren

Synthesis and biological evalu ...

Streptococcus pyogenes

Bioorg. Med. Chem.

17

3463-3470

2009

-

1

-

13

-

1

-

1

-

1

-

1

-

1

-

13

-

1

-

1

-

1

-

680145

Kuo

Degradation of complement 3 by ...

Streptococcus pyogenes

Infect. Immun.

76

1163-1169

2008

-

1

-

1

-

2

-

4

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

680146

Tsai

Streptococcal pyrogenic exotox ...

Streptococcus pyogenes

Infect. Immun.

76

1349-1357

2008

-

1

-

2

-

1

-

2

-

1

-

1

-

2

-

1

-

1

-

700243

Soederberg

The streptococcal protease Ide ...

Streptococcus pyogenes

Mol. Immunol.

45

3347-3353

2008

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

679955

Kuo

Abrogation of streptococcal py ...

Streptococcus pyogenes

Food Chem. Toxicol.

45

278-285

2007

-

1

-

1

-

5

-

1

-

1

-

1

-

1

-

1

-

1

-

681702

Luo

Streptococcal pyrogenic exotox ...

Streptococcus pyogenes

Kidney Int.

72

716-724

2007

-

1

-

1

-

1

-

6

-

1

-

1

-

1

-

1

-

1

-

682803

Cole

Role of group A Streptococcus ...

Streptococcus pyogenes M1 GAS, Streptococcus pyogenes M1 GAS HSC5

Proteomics

7

4488-4498

2007

1

-

1

-

2

-

6

-

4

-

1

-

1

-

2

-

4

-

667426

Tsao

Streptococcal pyrogenic exotox ...

Streptococcus pyogenes

Biochem. Biophys. Res. Commun.

339

779-784

2006

-

1

-

1

-

1

-

3

-

1

-

2

1

-

1

-

1

-

1

-

1

-

2

1

-

670124

Chiang-Ni

Streptococcal pyrogenic exotox ...

Streptococcus pyogenes

Med. Microbiol. Immunol.

195

55-63

2006

1

-

1

-

2

-

2

-

1

-

3

-

2

-

1

-

1

-

1

-

1

-

1

-

2

-

2

-

1

-

2

-

1

-

1

-

1

-

680712

Nooh

Streptococcal mitogenic exotox ...

Streptococcus pyogenes

J. Biol. Chem.

281

35281-35288

2006

-

1

-

3

-

3

-

1

-

3

-

667311

Anderson

The pro-sequence domain of str ...

Streptococcus pyogenes

Arch. Biochem. Biophys.

436

297-306

2005

-

1

-

1

-

2

-

3

-

1

-

2

1

-

1

-

1

-

1

-

1

-

2

-

1

-

2

1

-

1

-

668918

Wei

Impact of the SpeB protease on ...

Streptococcus pyogenes

Infect. Immun.

73

2040-2050

2005

-

1

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

670312

Kagawa

SpeB-Spi: a novel protease-inh ...

Streptococcus pyogenes, Streptococcus pyogenes B220

Mol. Microbiol.

57

650-666

2005

-

1

-

1

-

2

1

-

7

-

1

-

4

1

-

1

-

1

-

1

-

1

-

2

1

-

1

-

4

1

-

1

-

668772

Watts

-

Streptopain ...

Streptococcus pyogenes

Handbook of Proteolytic Enzymes (Barrett, A. J. , Rawlings, N. D. , Woessner, J. F. , eds. )Academic Press

2

1245-1249

2004

-

1

-

2

1

-

1

-

1

-

1

-

6

2

-

1

-

1

-

2

1

-

1

-

6

2

-

668904

Ohkuni

Studies of recombinant strepto ...

Streptococcus pyogenes

Indian J. Med. Res.

119 Suppl

33-36

2004

-

1

-

1

-

5

-

6

-

1

-

1

-

1

-

6

-

1

-

668911

Tsai

Streptococcal pyrogenic exotox ...

Streptococcus pyogenes, Streptococcus pyogenes A-20

Infect. Immun.

72

7055-7062

2004

-

1

-

1

-

1

-

2

-

4

-

1

-

4

1

-

1

-

1

-

1

-

1

-

2

-

1

-

4

1

-

1

-

670155

Nyberg

SpeB modulates fibronectin-dep ...

Streptococcus pyogenes

Microbiology

150

1559-1569

2004

-

1

-

2

-

1

-

4

-

1

-

1

-

1

-

2

-

4

-

1

-

1

-

651491

Eriksson

Cleavage of antigen-bound immu ...

Streptococcus sp., Streptococcus sp. T1BRB

Infect. Immun.

71

211-217

2003

-

2

-

2

-

4

-

2

-

4

-

650988

von Pawel-Rammingen

IdeS, a novel streptococcal cy ...

Streptococcus pyogenes

EMBO J.

21

1607-1615

2002

-

1

-

4

-

1

-

6

-

1

-

1

-

6

-

653648

Kagawa

Crystal structure of the zymog ...

Streptococcus pyogenes

Proc. Natl. Acad. Sci. USA

97

2235-2240

2000

-

1

-

6

-

1

-

81453

Doran

Autocatalytic processing of th ...

Streptococcus pyogenes, Streptococcus pyogenes B220

Eur. J. Biochem.

263

145-151

1999

-

1

-

1

-

5

-

1

-

11

-

1

-

1

-

1

-

1

-

11

-

1

-

81462

Stockbauer

A natural variant of the cyste ...

Streptococcus sp.

Proc. Natl. Acad. Sci. USA

96

242-247

1999

-

1

-

1

-

4

-

1

-

1

-

1

-

1

-

81470

Matsuka

Fibrinogen cleavage by the Str ...

Streptococcus pyogenes

Infect. Immun.

67

4326-4333

1999

-

1

-

1

-

2

-

1

-

2

-

81471

Lukomski

Extracellular cysteine proteas ...

Streptococcus pyogenes

Infect. Immun.

67

1779-1788

1999

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

81472

Eriksson

The superantigenic activity of ...

Streptococcus sp., Streptococcus sp. T10BW

FEMS Immunol. Med. Microbiol.

25

355-363

1999

-

1

-

3

-

2

-

1

-

2

-

81452

Ashbaugh

Molecular analysis of the role ...

Streptococcus sp.

J. Clin. Invest.

102

550-560

1998

-

3

-

1

-

7

-

1

-

3

-

1

-

1

-

81469

Tsai

Effect of group A streptococca ...

Streptococcus pyogenes

Infect. Immun.

66

1460-1466

1998

-

1

-

2

-

4

-

1

-

2

-

1

-

2

-

1

-

2

-

81463

Burns

Structure-function and pathoge ...

Streptococcus pyogenes

Adv. Exp. Med. Biol.

418

589-592

1997

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

81468

Chaussee

Temporal production of strepto ...

Streptococcus pyogenes

Infect. Immun.

65

1956-1959

1997

-

1

-

1

-

3

-

1

-

1

-

1

-

1

-

81466

Burns

Activation of a 66-kilodalton ...

Streptococcus pyogenes

Infect. Immun.

64

4744-4750

1996

-

1

-

5

-

1

-

1

-

1

-

81467

Herwald

Streptococcal cysteine protein ...

Streptococcus pyogenes

J. Exp. Med.

184

665-673

1996

-

1

-

1

-

1

-

6

-

2

-

1

-

1

-

1

-

2

-

81456

Berge

Streptococcal cysteine protein ...

Streptococcus pyogenes

J. Biol. Chem.

270

9862-9867

1995

-

1

-

1

-

1

-

4

-

1

-

4

-

1

-

1

-

1

-

1

-

4

-

81454

Green

Peptidyl diazomethyl ketones a ...

Streptococcus sp.

J. Biol. Chem.

256

1923-1928

1981

-

7

-

1

-

7

-

81455

Kortt

Primary structure of streptoco ...

Streptococcus sp.

J. Biol. Chem.

251

1941-1947

1976

-

1

-

2

-

1

-

81457

Tai

Primary structure of streptoco ...

Streptococcus sp.

J. Biol. Chem.

251

1955-1959

1976

-

1

-

2

-

1

-

81458

Kortt

On the mechanism of action of ...

Streptococcus sp.

Biochemistry

12

320-327

1973

-

2

-

2

-

2

-

81459

Kortt

On the mechanism of action of ...

Streptococcus sp.

Biochemistry

12

328-337

1973

-

8

-

2

-

10

-

7

-

8

-

10

-

7

-

81460

Kortt

On the mechanism of action of ...

Streptococcus sp.

Biochemistry

12

338-345

1973

-

3

6

-

2

-

2

-

6

-

3

-

6

-

2

-

6

-

81451

Liu

-

Streptococcal proteinase ...

Streptococcus sp.

The Enzymes, 3rd Ed. (Boyer, P. D. , ed. )

3

609-647

1971

3

-

1

-

5

8

-

2

-

1

-

1

-

1

-

1

11

-

3

8

-

1

-

3

-

1

-

5

-

8

-

8

-

2

-

1

-

1

-

1

11

-

3

8

-

1

-

81461

Elliott

-

Streptococcal proteinase ...

Streptococcus sp.

Methods Enzymol.

19

252-261

1970

1

-

4

-

1

-

1

-

1

-

1

3

-

1

-

4

-

1

-

1

-

1

3

-

81465

Gerwin

On the specificity of streptoc ...

Streptococcus sp.

J. Biol. Chem.

241

3331-3339

1966

-

1

-

2

-

3

-

1

-

3

-

81464

Liu

Streptococcal proteinase: the ...

Streptococcus pyogenes

J. Biol. Chem.

240

1138-1142

1965

-

2

-

1

-

1

-

The streptococcal cysteine protease SpeB is not a natural immunoglobulin-cleaving enzyme

Data extracted from this reference: