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Literature summary for 3.4.22.10 extracted from

  • Nooh, M.M.; Aziz, R.K.; Kotb, M.; Eroshkin, A.; Chuang, W.J.; Proft, T.; Kansal, R.
    Streptococcal mitogenic exotoxin, SmeZ, is the most susceptible M1T1 streptococcal superantigen to degradation by the streptococcal cysteine protease, SpeB (2006), J. Biol. Chem., 281, 35281-35288.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
E-64 0.028 mM Streptococcus pyogenes

Organism

Organism UniProt Comment Textmining
Streptococcus pyogenes
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information does not cleave streptococcal mitogenic exotoxins SpeA and SpeJ Streptococcus pyogenes ?
-
?
streptococcal mitogenic exotoxin SmeZ + H2O cleaves between glutamate and glycine residues Streptococcus pyogenes ?
-
?
streptococcal mitogenic exotoxin SpeG + H2O partial degradation, SpeB cleaves between glutamate and glycine residues Streptococcus pyogenes ?
-
?

Synonyms

Synonyms Comment Organism
SpeB
-
Streptococcus pyogenes