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Literature summary for 3.4.22.1 extracted from

  • Lee, K.S.; Kim, B.Y.; Choo, Y.M.; Yoon, H.J.; Kang, P.D.; Woo, S.D.; Sohn, H.D.; Roh, J.Y.; Gui, Z.Z.; Je, Y.H.; Jin, B.R.
    Expression profile of cathepsin B in the fat body of Bombyx mori during metamorphosis (2009), Comp. Biochem. Physiol. B, 154, 188-194.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
CatB DNA and amino acid sequence determination and analysis, recombinant expression in Spodoptera frugiperda cell line Sf9 using the baculovirus expression vector system with the Autographa californica nucleopolyhedrovirus Bombyx mori

Protein Variants

Protein Variants Comment Organism
additional information BmCatB RNAi treatment results in an arrest of the larval-pupal transformation. RNAi-mediated BmCatB knockdown sustains the expression of BmCatD during the larval-pupal transformation. On the other hand, when BmCatD is inhibited via RNAi, the expression of BmCatB is upregulated, overview Bombyx mori

Localization

Localization Comment Organism GeneOntology No. Textmining
lysosome
-
Bombyx mori 5764
-

Organism

Organism UniProt Comment Textmining
Bombyx mori
-
-
-

Purification (Commentary)

Purification (Comment) Organism
recombinant CatB from Sf9 insect cells Bombyx mori

Source Tissue

Source Tissue Comment Organism Textmining
fat body primarily, expression profile of cathepsin B in the fat body during metamorphosis, overview. CatB shows a high expression level during the larval-pupal transformation Bombyx mori
-

Synonyms

Synonyms Comment Organism
CatB
-
Bombyx mori

Expression

Organism Comment Expression
Bombyx mori when BmCatD is inhibited via RNAi, the expression of BmCatB is upregulated up

General Information

General Information Comment Organism
malfunction BmCatB RNAi treatment results in an arrest of the larval-pupal transformation. RNAi-mediated BmCatB knockdown sustains the expression of BmCatD during the larval-pupal transformation. On the other hand, when BmCatD is inhibited via RNAi, the expression of BmCatB is upregulated Bombyx mori
physiological function BmCatB is involved in the programmed cell death of the fat body during metamorphosis, and CatB and CatD contribute to the metamorphosis Bombyx mori