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Literature summary for 3.4.22.1 extracted from

  • Pan, X.; Tan, N.; Zeng, G.; Zhang, Y.; Jia, R.
    Amentoflavone and its derivatives as novel natural inhibitors of human Cathepsin B (2005), Bioorg. Med. Chem., 13, 5819-5825.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
4'''-methylamentoflavone IC50: 0.00168 mM Homo sapiens
7'',4'''-dimethylamentoflavone IC50: 0.00055 mM Homo sapiens
amentoflavone IC50: 0.00175 mM Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P07858
-
-

Synonyms

Synonyms Comment Organism
CatB
-
Homo sapiens
cathepsin B
-
Homo sapiens

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.00055
-
IC50: 0.00055 mM Homo sapiens 7'',4'''-dimethylamentoflavone
0.00168
-
IC50: 0.00168 mM Homo sapiens 4'''-methylamentoflavone
0.00175
-
IC50: 0.00175 mM Homo sapiens amentoflavone