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Literature summary for 3.4.21.B45 extracted from

  • Deraison, C.; Bonnart, C.; Lopez, F.; Besson, C.; Robinson, R.; Jayakumar, A.; Wagberg, F.; Brattsand, M.; Hachem, J.P.; Leonardsson, G.; Hovnanian, A.
    LEKTI fragments specifically inhibit KLK5, KLK7, and KLK14 and control desquamation through a pH-dependent interaction (2007), Mol. Biol. Cell, 18, 3607-3619.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.B45

Inhibitors

Inhibitors Comment Organism Structure
lympho-epithelial Kazal type inhibitor fragment D5
-
 Homo sapiens
lympho-epithelial Kazal type inhibitor fragment D8-D11
-
 Homo sapiens
lympho-epithelial Kazal type inhibitor fragment D9-D15
-
 Homo sapiens
additional information not inhibited by lympho-epithelial Kazal type inhibitor fragments D1 and D6 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.75
-
 L-Pro-Phe-Arg-p-nitroanilide in 0.1 M Tris, 0.5 M NaCl, pH 8 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epidermis
-
 Homo sapiens
-
keratinocyte
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Pro-Phe-Arg-p-nitroanilide + H2O
-
 Homo sapiens L-Pro-Phe-Arg + p-nitroaniline
-
 ?

Synonyms

Synonyms Comment Organism
kallikrein 14
-
 Homo sapiens
KLK14
-
 Homo sapiens
SCTE
-
 Homo sapiens

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0000031
-
 lympho-epithelial Kazal type inhibitor fragment D8-11
-
 Homo sapiens
0.0000176
-
 lympho-epithelial Kazal type inhibitor fragment D5
-
 Homo sapiens
0.0000523
-
 lympho-epithelial Kazal type inhibitor fragment D9-15
-
 Homo sapiens