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Literature summary for 3.4.21.B42 extracted from

  • Bi, X.; He, H.; Ye, Y.; Dai, Q.; Han, Z.; Liang, Y.; Zhong, W.
    Association of TMPRSS2 and KLK11 gene expression levels with clinical progression of human prostate cancer (2010), Med. Oncol., 27, 145-151.
    View publication on PubMed

Application

Application Comment Organism
medicine the down-regulation of KLK11 gene in advanced and more aggressive tumors opens the feasibility of being used as biomarker distinguishing the tumor aggressiveness and prognostic indicators for human prostate cancer Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Homo sapiens
-
prostate cancer cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
brain-type KLK11 isoform Homo sapiens
kallikrein 11
-
Homo sapiens
KLK11
-
Homo sapiens
prostate-type KLK11 isoform Homo sapiens

Expression

Organism Comment Expression
Homo sapiens regarding prostate-type KLK11, there is a significant association between lower expression and higher tumor stage down
Homo sapiens both isoforms of KLK11 (prostate-type and brain-type) are significantly higher in cancer tissues compared with their normal counterparts up