Cloned (Comment) | Organism |
---|---|
- |
Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
Aprotinin | 93% inactivation at 0.015 mM | Homo sapiens | |
benzamidine | 56% inactivation at 27 mM | Homo sapiens | |
bikunin | subunit of inter-alpha-trypsin inhibitor complex, physiologic inhibitor | Homo sapiens | |
human blood plasma | - |
Homo sapiens | |
inter-alpha-trypsin inhibitor complex | physiologic inhibitor | Homo sapiens | |
Kunitz-type inhibitor aprotinin | - |
Homo sapiens | |
leupeptin | 22% inactivation at 0.2 mM | Homo sapiens | |
PefablocSC | 94% inactivation at 1 mM | Homo sapiens | |
Phe-Pro-Arg-chloromethyl ketone | complete inactivation at 0.1 mM | Homo sapiens | |
phenylmethylsulfonyl fluoride | complete inactivation at 2 mM | Homo sapiens | |
second carboxy-terminal Kunitz-type domain of bikunin | physiologic inhibitor | Homo sapiens |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.14 | - |
Nalpha-benzyloxycarbonyl-L-Arg-thiobenzyl ester | pH 7.6 | Homo sapiens | |
1.7 | - |
Nalpha-benzyloxycarbonyl-L-Lys-thiobenzyl ester | pH 7.6 | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Protein + H2O | Homo sapiens | - |
? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
lymphocyte | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | cleaves synthetic thiobenzyl ester substrates after Lys and Arg, no substrates for the mature enzyme: Boc-Ala-Ala-Met-thiobenzyl ester and Boc-Ala-Ala-Asp-thiobenzyl ester | Homo sapiens | ? | - |
? | |
Nalpha-benzyloxycarbonyl-L-Arg-thiobenzyl ester | - |
Homo sapiens | ? | - |
? | |
Nalpha-benzyloxycarbonyl-L-Lys-thiobenzyl ester | - |
Homo sapiens | ? | - |
? | |
Protein + H2O | - |
Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
granzyme 3 | - |
Homo sapiens |
lymphocyte tryptase 2 | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
8.2 | 8.6 | - |
Homo sapiens |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.000022 | - |
second carboxy-terminal Kunitz-type domain of bikunin | pH 7.6 | Homo sapiens | |
0.00005 | - |
bikunin | pH 7.6 | Homo sapiens | |
0.000064 | - |
inter-alpha-trypsin inhibitor complex | pH 7.6 | Homo sapiens |