Protein Variants | Comment | Organism |
---|---|---|
F26A/P27A/S28A/P29A | can form heterodimers and is recognized by ClpXP protease | Escherichia coli |
L9A/R10A/E11A/I12A | heterodimer with UmuD' displays a significant increase in stability | Escherichia coli |
General Stability | Organism |
---|---|
highly purified UmuD/D' heterodimer is degraded in the presence of ATP, ClpP and ClpX, no degradation occurs when ClpX is omitted | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Posttranslational Modification | Comment | Organism |
---|---|---|
proteolytic modification | inactive UmuD is posttranslationally activated by a RecA-mediated cleavage that yields UmuD' | Escherichia coli |
Subunits | Comment | Organism |
---|---|---|
dimer | although UmuD and UmuD' form homodimers, they preferentially form heterodimers, SDS-PAGE | Escherichia coli |