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Literature summary for 3.4.21.B25 extracted from

  • Mori, K.; Kii, S.; Tsuji, A.; Nagahama, M.; Imamaki, A.; Hayashi, K.; Akamatsu, T.; Nagamune, H.; Matsuda, Y.
    A novel human PACE4 isoform, PACE4E is an active processing protease containing a hydrophobic cluster at the carboxy terminus (1997), J. Biochem., 121, 941-948.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
isoform PACE4E-I and truncated mutant, expressed in COS-1 cells Homo sapiens
isoform PACE4E-II expressed in COS-1 cells Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
105000
-
SDS-PAGE, mature protein Homo sapiens
112000
-
SDS-PAGE, precursor protein Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P29122
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
proteolytic modification precursor form is cleaved into a mature form Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
Homo sapiens
-
cerebellum
-
Homo sapiens
-
pituitary gland
-
Homo sapiens
-
placenta
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
von Willebrand factor precursor + H2O
-
Homo sapiens mature von Willebrand factor + ?
-
?

Synonyms

Synonyms Comment Organism
PACE4
-
Homo sapiens