Activating Compound | Comment | Organism | Structure |
---|---|---|---|
androgens | up-regulation of gene expression | Homo sapiens | |
progestins | - |
Homo sapiens | |
progestins | up-regulation of gene expression | Homo sapiens |
Cloned (Comment) | Organism |
---|---|
DNA sequence determination and analysis, chromosome mapping and genomic organization | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
polypeptide + H2O | Homo sapiens | - |
peptides | - |
? | |
polypeptide + H2O | Homo sapiens | enzyme is regulated by steroid hormones | peptides | - |
? | |
polypeptide + H2O | Homo sapiens | enzyme may be involved in the pathogenesis and/or progression of prostate, breast, and possibly other malgnancies | peptides | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q9Y5K2 | gene KLK-L1 | - |
Homo sapiens | Q9Y5K2 | gene prostase | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
adrenal gland | high expression level | Homo sapiens | - |
bone marrow | low expression level | Homo sapiens | - |
brain | low expression level, not in fetal brain | Homo sapiens | - |
breast | - |
Homo sapiens | - |
BT-474 cell | - |
Homo sapiens | - |
cerebellum | low expression level | Homo sapiens | - |
colon | medium expression level | Homo sapiens | - |
lung | low expression level | Homo sapiens | - |
mammary gland | medium expression level | Homo sapiens | - |
additional information | - |
Homo sapiens | - |
additional information | no expression in stomach, heart, spleen, placenta, liver, pancrease, kidney, skeletal muscle, small intestine | Homo sapiens | - |
prostate | - |
Homo sapiens | - |
prostate | high expression level | Homo sapiens | - |
salivary gland | low expression level | Homo sapiens | - |
spinal cord | medium expression level | Homo sapiens | - |
testis | high expression level | Homo sapiens | - |
thymus | low expression level | Homo sapiens | - |
thyroid gland | high expression level | Homo sapiens | - |
trachea | low expression level | Homo sapiens | - |
uterus | high expression level | Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
polypeptide + H2O | - |
Homo sapiens | peptides | - |
? | |
polypeptide + H2O | enzyme is regulated by steroid hormones | Homo sapiens | peptides | - |
? | |
polypeptide + H2O | enzyme may be involved in the pathogenesis and/or progression of prostate, breast, and possibly other malgnancies | Homo sapiens | peptides | - |
? |