Literature summary for 3.4.21.98 extracted from

Dietz, J.; Lutz, T.; Knecht, G.; Gute, P.; Berkowski, C.; Lange, C.M.; Khaykin, P.; Stephan, C.; Brodt, H.R.; Herrmann, E.; Zeuzem, S.; Sarrazin, C.
Evolution and function of the HCV NS3 protease in patients with acute hepatitis C and HIV coinfection (2015), Virology, 485, 213-222 .

Search for more literature for 3.4.21.98

Cloned(Commentary)

Cloned (Comment)	Organism
HCV NS3 sequence comparisons and phylogenetic analysis	Hepacivirus C

Organism

Organism	UniProt	Comment	Textmining
Hepacivirus C	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
additional information	baseline NS3 quasispecies diversity and complexity is higher in acutely infected subjects compared to a chronic hepatitis C control group. Both parameters are comparable in patients with spontaneous clearance versus treatment-induced acute hepatitis C or development of chronic hepatitis C. Longitudinal NS3 quasispecies kinetics show a trend to a decreasing diversity and complexity within 4 weeks in patients with spontaneous clearance compared to the other groups	Hepacivirus C	-

Synonyms

Synonyms	Comment	Organism
HCV NS3 protease	-	Hepacivirus C
NS3	-	Hepacivirus C

General Information

General Information	Comment	Organism
evolution	phylogenetic analyses of NS3 proteases sequences	Hepacivirus C
additional information	baseline NS3 quasispecies diversity and complexity is higher in acutely infected subjects compared to a chronic hepatitis C control group. Both parameters are comparable in patients with spontaneous clearance versus treatment-induced acute hepatitis C or development of chronic hepatitis C. Longitudinal NS3 quasispecies kinetics show a trend to a decreasing diversity and complexity within 4 weeks in patients with spontaneous clearance compared to the other groups. Spontaneous clearance of acute hepatitis C, baseline clinical parameters of 82 patients with an acute hepatitis C and HIV coinfection, overview	Hepacivirus C

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Release 2023.1 (January 2023)