Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli cells | Hepacivirus C |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
BILN-2061 | - |
Hepacivirus C | |
MK-7009 | i.e. (1R,21S,24S)-21-tert-butyl-N-((1R,2R)-1-[[(cyclopropylsulfonyl)amino]carbonyl]-2-ethylcyclopropyl)-16,16-dimethyl-3,19,22-trioxo-2,18-dioxa-4,20,23-triazatetracyclo[21.2.1.14,70.06,11]heptacosa-6,8,10-triene-24-carboxamide, potent and selective inhibitor of hepatitis C virus NS3/4A protease | Hepacivirus C | |
SCH-503034 | - |
Hepacivirus C | |
VX-950 | - |
Hepacivirus C |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Hepacivirus C | - |
- |
- |
Purification (Comment) | Organism |
---|---|
- |
Hepacivirus C |
Synonyms | Comment | Organism |
---|---|---|
NS3 | - |
Hepacivirus C |
NS3 protease | - |
Hepacivirus C |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00000006 | - |
MK-7009 | NS3/4A genotype 1b | Hepacivirus C | |
0.00000007 | - |
MK-7009 | NS3/4A genotype 1a | Hepacivirus C | |
0.000001 | - |
MK-7009 | NS3/4A genotype 2a | Hepacivirus C | |
0.0000014 | - |
MK-7009 | NS3/4A genotype 2b | Hepacivirus C | |
0.000003 | - |
BILN-2061 | NS3/4A genotype 1b | Hepacivirus C | |
0.0000081 | - |
BILN-2061 | NS3/4A genotype 1a | Hepacivirus C | |
0.000021 | - |
SCH-503034 | NS3/4A genotype 1a | Hepacivirus C | |
0.000021 | - |
SCH-503034 | NS3/4A genotype 2b | Hepacivirus C | |
0.000025 | - |
SCH-503034 | NS3/4A genotype 2a | Hepacivirus C | |
0.000028 | - |
SCH-503034 | NS3/4A genotype 1b | Hepacivirus C | |
0.000042 | - |
VX-950 | NS3/4A genotype 2b | Hepacivirus C | |
0.000054 | - |
VX-950 | NS3/4A genotype 2a | Hepacivirus C | |
0.00007 | - |
BILN-2061 | NS3/4A genotype 2a | Hepacivirus C | |
0.000093 | - |
VX-950 | NS3/4A genotype 1b | Hepacivirus C | |
0.00013 | - |
VX-950 | NS3/4A genotype 1a | Hepacivirus C | |
0.00061 | - |
BILN-2061 | NS3/4A genotype 2b | Hepacivirus C |