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Literature summary for 3.4.21.97 extracted from
- Cleavage of human cytomegalovirus protease pUL80a at internal and cryptic sites is not essential but enhances infectivity (2005), J. Virol., 79, 12961-12968.
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Human betaherpesvirus 5 | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| proteolytic modification | the enzyme contains an internal (I) cleavage site. Blocking this site for cleavage in I- mutant virus shows increased amounts of a fragment produced by cleavage at the nearby cryptic site, suggesting that its replication may bypass the I-site block by using the C site as an alternative cleavage pathway. I-site cleavage destabilizes assemblin and its fragments, whereas C-site cleavage does not | Human betaherpesvirus 5 |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| cytomegalovius maturational protease | - |
Human betaherpesvirus 5 |
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