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Literature summary for 3.4.21.97 extracted from

  • geitmann, M.; Danielson, E.H.
    Studies of substrate-induced conformational changes in human cytomegalovirus protease using optical biosensor technology (2004), Anal. Biochem., 332, 203-214.
    View publication on PubMed
Search for more literature for 3.4.21.97

Inhibitors

Inhibitors Comment Organism Structure
additional information the enzyme is inactivated by chemical crosslinking, indicating that the structural flexibility is essential for this enzyme Human betaherpesvirus 5

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.083
-
 4-(4'-dimethylaminophenylazo)benzoyl-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-5-((2'-aminoethyl)amino)-naphthalene-1-sulfonic acid pH 7.4, immobilized enzyme Human betaherpesvirus 5
0.159
-
 4-(4'-dimethylaminophenylazo)benzoyl-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-5-((2'-aminoethyl)amino)-naphthalene-1-sulfonic acid pH 7.4, enzyme in solution Human betaherpesvirus 5

Organism

Organism UniProt Comment Textmining
Human betaherpesvirus 5
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4-(4'-dimethylaminophenylazo)benzoyl-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-5-((2'-aminoethyl)amino)-naphthalene-1-sulfonic acid + H2O studies of substrate-induced conformational changes in human cytomegalovirus protease using optical biosensor technology Human betaherpesvirus 5 4-(4'-dimethylaminophenylazo)benzoyl-Arg-Gly-Val-Val-Asn-Ala + Ser-Ser-Arg-Leu-Ala-5-((2'-aminoethyl)amino)-naphthalene-1-sulfonic acid
-
 ?

Synonyms

Synonyms Comment Organism
human cytomegalovirus protease
-
 Human betaherpesvirus 5

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
additional information
-
 additional information the turnover number for 4-(4'-dimethylaminophenylazo)benzoyl-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-(2'-aminoethyl)amino-naphthalene-1-sulfonic acid is less than 0.001/s, immobilized crosslinked enzyme Human betaherpesvirus 5
0.035
-
 4-(4'-dimethylaminophenylazo)benzoyl-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-5-((2'-aminoethyl)amino)-naphthalene-1-sulfonic acid pH 7.4, enzyme in solution Human betaherpesvirus 5
0.046
-
 4-(4'-dimethylaminophenylazo)benzoyl-Arg-Gly-Val-Val-Asn-Ala-Ser-Ser-Arg-Leu-Ala-5-((2'-aminoethyl)amino)-naphthalene-1-sulfonic acid pH 7.4, immobilized enzyme Human betaherpesvirus 5