Crystallization (Comment) | Organism |
---|---|
hanging-drop vapor diffusion method, crystal structure of the wild-typelike mutant enzyme A143Q in complex with peptidomimetic inhibitors, crystal structure of peptidomimetic inhibitor in complex with the E31R mutant enzyme | Human betaherpesvirus 5 |
Protein Variants | Comment | Organism |
---|---|---|
A143Q/E31R | the ratio of turnover number to Km-value is 44.6fold lower than that for the wild-typelike mutant A143Q | Human betaherpesvirus 5 |
A143Q/E31S | the ratio of turnover number to Km-value is 4.8fold lower than that for the wild-typelike mutant A143Q | Human betaherpesvirus 5 |
A143Q/R137E | the ratio of turnover number to Km-value is 6.3fold lower than that for the wild-typelike mutant A143Q | Human betaherpesvirus 5 |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-N-(1-benzyl-2-oxo-2-thiazol-2-yl-ethyl)-acetamide | - |
Human betaherpesvirus 5 |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Human betaherpesvirus 5 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
human cytomegalovirus protease | - |
Human betaherpesvirus 5 |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
additional information | - |
additional information | - |
Human betaherpesvirus 5 | |
additional information | - |
2-[5-Amino-2-(4-fluoro-phenyl)-6-oxo-6H-pyrimidin-1-yl]-N-(1-benzyl-2-oxo-2-thiazol-2-yl-ethyl)-acetamide | - |
Human betaherpesvirus 5 |