Cloned (Comment) | Organism |
---|---|
overexpressed in Chinese hamster ovary cells supertransfected with rat cDNA 7B2 | Mus musculus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.032 | - |
pGlu-Arg-Thr-Lys-Arg-methylcoumarin amide | pH 5.0, 37°C | Mus musculus | |
0.077 | - |
leumorphin | pH 5.0, 37°C | Mus musculus | |
0.079 | - |
dynorphin A 1-17 | pH 5.0, 37°C | Mus musculus | |
0.1 | - |
dynorphin AB 1-32 | pH 5.0, 37°C | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
mouse | - |
Rattus norvegicus | - |
rat, Sprague-Dawley | - |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Mus musculus |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.015 | - |
- |
Mus musculus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Cbz-Arg-Ser-Lys-Arg-aminomethylcoumarin + H2O | - |
Mus musculus | ? | - |
? | |
dynorphin A 1-17 + H2O | - |
Mus musculus | ? | - |
? | |
dynorphin AB 1-32 + H2O | - |
Mus musculus | ? | - |
? | |
leumorphin + H2O | - |
Mus musculus | ? | - |
? | |
prodynorphin + H2O | - |
Mus musculus | dynorphin A 1-17 + dynorphin B 1-13 + alpha-neo-endorphin + C-peptide + dynorphin A 1-8 + ? | - |
? |
Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
---|---|---|---|
42.5 | - |
no significant loss of PC2 activity is observed below 42.5°C | Mus musculus |