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Literature summary for 3.4.21.93 extracted from

  • Li, Q.L.; Jansen, E.; Brent, G.A.; Friedman, T.C.
    Regulation of prohormone convertase 1 (PC1) by thyroid hormone (2001), Am. J. Physiol. Endocrinol. Metab., 280, E160-170.
    View publication on PubMed
Search for more literature for 3.4.21.93

Cloned(Commentary)

Cloned (Comment) Organism
hPC1-luciferase fusion gene expression plasmid Homo sapiens

Inhibitors

Inhibitors Comment Organism Structure
profurin 54-62 SPHRPRHSR
-
 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens key enzyme capable of processing a variety of prohormones to their bioactive forms ?
-
 ?
additional information Rattus norvegicus key enzyme capable of processing a variety of prohormones to their bioactive forms ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-
Rattus norvegicus
-
 rat, Sprague-Dawley
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information key enzyme capable of processing a variety of prohormones to their bioactive forms Homo sapiens ?
-
 ?
additional information key enzyme capable of processing a variety of prohormones to their bioactive forms Rattus norvegicus ?
-
 ?

Synonyms

Synonyms Comment Organism
PC1
-
 Homo sapiens
PC1
-
 Rattus norvegicus
prohormone convertase 1
-
 Homo sapiens
prohormone convertase 1
-
 Rattus norvegicus

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.0735
-
 profurin 54-62 SPHRPRHSR pH 7.0, 25°C Homo sapiens