Literature summary for 3.4.21.92 extracted from

Lee, B.; Kim, M.; Song, H.
Structural insights into the conformational diversity of ClpP from Bacillus subtilis (2011), Mol. Cells, 32, 589-595.

Search for more literature for 3.4.21.92

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli using a His-tagged fusion protein	Bacillus subtilis

Crystallization (Commentary)

Crystallization (Comment)	Organism
crystal structure of ClpP from Bacillus subtilis shows a significantly compressed shape along the axial direction. A portion of the handle regions comprising the heptameric ring-ring contacts shows structural transition from an ordered to a disordered state, which triggers the large conformational change from an extended to an overall compressed structure. Along with this structural change, 14 side pores are generated for product release and the catalytic triad adopts an inactive orientation	Bacillus subtilis

Crystallization (Comment)

Organism

crystal structure of ClpP from Bacillus subtilis shows a significantly compressed shape along the axial direction. A portion of the handle regions comprising the heptameric ring-ring contacts shows structural transition from an ordered to a disordered state, which triggers the large conformational change from an extended to an overall compressed structure. Along with this structural change, 14 side pores are generated for product release and the catalytic triad adopts an inactive orientation

Bacillus subtilis

Inhibitors

Inhibitors	Comment	Organism	Structure
diisopropylfluorophosphate	-	Bacillus subtilis

Organism

Organism	UniProt	Comment	Textmining
Bacillus subtilis	P80244	-	-

Purification (Commentary)

Purification (Comment)	Organism
using Ni-NTA chromatography	Bacillus subtilis

Synonyms

Synonyms	Comment	Organism
BsClpP	-	Bacillus subtilis

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)