Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
COMK + H2O | ClpCP, MecA required | Bacillus subtilis | ? | - |
? | |
MurAA + H2O | MecA not required for degradation | Bacillus subtilis | ? | - |
? | |
RsiW + H2O | ClXCP, AA at C-terminal as degradation tag | Bacillus subtilis | ? | - |
? | |
Sda + H2O | ClpXP, VSS at C-terminal as degradation tag | Bacillus subtilis | ? | - |
? | |
SpollAB + H2O | ClpCP, LCN at C-terminal as degradation tag, MecA not required, production of ClpP is strongly increased in response to heat shock or other stress signals, ClpP removes heat damaged proteins | Bacillus subtilis | ? | - |
? | |
Spx + H2O | ClpCP, MecA or YpbH required for degradation | Bacillus subtilis | ? | - |
? | |
Spx + H2O | ClpXP, LAN at C-terminal as degradation tag, MecA not required | Bacillus subtilis | ? | - |
? | |
SsrA tagged proteins + H2O | ClpXP, AA at C-terminal as degradation tag | Bacillus subtilis | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | 1400 ClpX hexamers, 250 ClpC heaxmers and 100 ClpE hexamers and 1200 ClpP tetramers are found in one cell during exponential growth at 37°C | Bacillus subtilis |
Synonyms | Comment | Organism |
---|---|---|
ClpP | proteolytic complex | Bacillus subtilis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | MecA facilitates ClpC oligomerization into a complex containing both ClpC and MecA. Formation of this complex is a prerequisite for all ClpC mediated activities, including ATPase activity, substrate recognition and interaction with ClpP | Bacillus subtilis |