Literature summary for 3.4.21.91 extracted from

Chen, W.N.; Loscha, K.V.; Nitsche, C.; Graham, B.; Otting, G.
The dengue virus NS2B-NS3 protease retains the closed conformation in the complex with BPTI (2014), FEBS Lett., 588, 2206-2211.

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Crystallization (Commentary)

Crystallization (Comment)	Organism
pseudocontact shifts from a lanthanide tag show that NS2Bc remains in the closed conformation also in the complex with bovine pancreatic trypsin inhibitor. The closed conformation is the best template for drug discovery	Dengue virus

Inhibitors

Inhibitors	Comment	Organism	Structure
Bovine pancreatic trypsin inhibitor	pseudocontact shifts from a lanthanide tag show that NS2Bc remains in the closed conformation also in the complex with	Dengue virus

Organism

Organism	UniProt	Comment	Textmining
Dengue virus	Q91H74	type 2	-

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Release 2023.1 (January 2023)