Literature summary for 3.4.21.91 extracted from

Ang, M.J.; Yong, G.H.; Poulsen, A.; Then, S.W.; Li, Z.; Joy, J.; Hill, J.; Chia, C.S.
Substrate-based peptidomimetic inhibitors of the Murray Valley encephalitis virus NS2B/NS3 serine protease: a P1-P4 SAR study (2013), Eur. J. Med. Chem., 68, 72-80.

Search for more literature for 3.4.21.91

Inhibitors

Inhibitors	Comment	Organism	Structure
N2-(biphenyl-3-ylacetyl)-L-lysyl-N-[(1-carbamimidoylpiperidin-4-yl)methyl]-L-lysinamide	C-terminal agmatine peptidomimetic inhibitor, competitive	Murray Valley encephalitis virus

Organism

Organism	UniProt	Comment	Textmining
Murray Valley encephalitis virus	-	-	-

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.0025	-	N2-(biphenyl-3-ylacetyl)-L-lysyl-N-[(1-carbamimidoylpiperidin-4-yl)methyl]-L-lysinamide	pH 8.0, 25°C	Murray Valley encephalitis virus

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.0049	-	pH 8.0, 25°C	Murray Valley encephalitis virus	N2-(biphenyl-3-ylacetyl)-L-lysyl-N-[(1-carbamimidoylpiperidin-4-yl)methyl]-L-lysinamide

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)