Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | cytoplasmic localization with membrane association | Dengue virus | - |
- |
additional information | cytoplasmic localization with membrane association | Yellow fever virus | - |
- |
additional information | cytoplasmic localization with membrane association | Flavivirus sp. | - |
- |
additional information | viral enzyme acting in cytoplasma of host cell | Dengue virus | - |
- |
additional information | viral enzyme acting in cytoplasma of host cell | Yellow fever virus | - |
- |
additional information | viral enzyme acting in cytoplasma of host cell | Flavivirus sp. | - |
- |
additional information | viral enzyme (NS3) | Dengue virus | - |
- |
additional information | viral enzyme (NS3) | Yellow fever virus | - |
- |
additional information | viral enzyme (NS3) | Flavivirus sp. | - |
- |
additional information | NS2B is membrane component of viral replication process, presumably responsible for membrane localization of NS3 | Dengue virus | - |
- |
additional information | NS2B is membrane component of viral replication process, presumably responsible for membrane localization of NS3 | Yellow fever virus | - |
- |
additional information | NS2B is membrane component of viral replication process, presumably responsible for membrane localization of NS3 | Flavivirus sp. | - |
- |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
68000 | 70000 | Flavivirus sp., predicted MW of N3 protein | Flavivirus sp. |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
Flavivirus sp. polyproteins + H2O | Flavivirus sp. | involved in processing of downstream nonstructural proteins of the virus polyprotein | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Dengue virus | - |
i.e. DEN2 | - |
Flavivirus sp. | - |
JE, KUN, MVE, SLE, WN, YF and TRE | - |
Yellow fever virus | - |
i.e. YF | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Dengue virus polyprotein + H2O | - |
Dengue virus | Dengue virus proteins NS3 and NS5 | - |
? | |
Flavivirus sp. polyproteins + H2O | cleavage sites consist of Lys-Arg, Arg-Lys or Arg-Arg (Dengue virus: Gln-Arg) usually followed by Gln, Ala or Ser, cleavage sites: NS2A/2B, NS2B/3, NS3/4A (not SLE virus), NS4B/5 (not SLE virus) | Flavivirus sp. | ? | - |
? | |
Flavivirus sp. polyproteins + H2O | involved in processing of downstream nonstructural proteins of the virus polyprotein | Flavivirus sp. | ? | - |
? | |
additional information | amino-terminal third of NS3 acts as serine protease on nonstructural viral proteins | Dengue virus | ? | - |
? | |
additional information | amino-terminal third of NS3 acts as serine protease on nonstructural viral proteins | Yellow fever virus | ? | - |
? | |
additional information | amino-terminal third of NS3 acts as serine protease on nonstructural viral proteins | Flavivirus sp. | ? | - |
? | |
Yellow fever virus protein + H2O | - |
Yellow fever virus | ? | - |
? |