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Literature summary for 3.4.21.9 extracted from

  • Grant, D.A.W.; Hermon-Taylor, J.
    Enterokinase (1984), Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. ), 5, 143-155.
No PubMed abstract available

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Trypsinogen + H2O Sus scrofa
-
?
-
?
Trypsinogen + H2O Bos taurus
-
?
-
?
Trypsinogen + H2O Homo sapiens rapid activation of trypsinogen in pancreatic juice. The enzyme has a key permissive role in protein digestion and plays an essential part in the zymogen mechanism that protects the pancreas from self-destruction ?
-
?

Organism

Organism UniProt Comment Textmining
Bos taurus
-
-
-
Homo sapiens
-
-
-
Sus scrofa
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
side-chain modification
-
Bos taurus
side-chain modification glycosylated mainly with N-linked carbohydrate chains of the triantennary and tetraantennary complex type Sus scrofa
side-chain modification contains more than 57% carbohydrate per weight Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
duodenum
-
Sus scrofa
-
duodenum
-
Bos taurus
-
duodenum localized in the brush-border of the enterocytes lining the duodenum and the first 10-20 cm of the small intestine Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzoyl-Arg ethyl ester + H2O
-
Homo sapiens benzoyl-Arg + ethanol
-
?
benzoyl-Arg ethyl ester + H2O
-
Sus scrofa benzoyl-Arg + ethanol
-
?
benzoyl-Arg ethyl ester + H2O
-
Bos taurus benzoyl-Arg + ethanol
-
?
Gly-Asp-Asp-Asp-Asp-Lys-2-naphthylamide + H2O
-
Homo sapiens Gly-Asp-Asp-Asp-Asp-Lys + 2-naphthylamine
-
?
Gly-Asp-Asp-Asp-Asp-Lys-2-naphthylamide + H2O
-
Sus scrofa Gly-Asp-Asp-Asp-Asp-Lys + 2-naphthylamine
-
?
Gly-Asp-Asp-Asp-Asp-Lys-2-naphthylamide + H2O
-
Bos taurus Gly-Asp-Asp-Asp-Asp-Lys + 2-naphthylamine
-
?
Nalpha-acetyltrypsinogen + H2O
-
Homo sapiens Nalpha-acetylactivation peptides + trypsin
-
?
Nalpha-acetyltrypsinogen + H2O
-
Sus scrofa Nalpha-acetylactivation peptides + trypsin
-
?
Nalpha-acetyltrypsinogen + H2O
-
Bos taurus Nalpha-acetylactivation peptides + trypsin
-
?
Tosyl-Arg methyl ester + H2O
-
Homo sapiens Tosyl-Arg + methanol
-
?
Tosyl-Arg methyl ester + H2O
-
Sus scrofa Tosyl-Arg + methanol
-
?
Tosyl-Arg methyl ester + H2O
-
Bos taurus Tosyl-Arg + methanol
-
?
tosyl-Lys methyl ester + H2O
-
Homo sapiens tosyl-Lys + methanol
-
?
tosyl-Lys methyl ester + H2O
-
Sus scrofa tosyl-Lys + methanol
-
?
tosyl-Lys methyl ester + H2O
-
Bos taurus tosyl-Lys + methanol
-
?
Trypsinogen + H2O
-
Sus scrofa ?
-
?
Trypsinogen + H2O
-
Bos taurus ?
-
?
Trypsinogen + H2O rapid activation of trypsinogen in pancreatic juice. The enzyme has a key permissive role in protein digestion and plays an essential part in the zymogen mechanism that protects the pancreas from self-destruction Homo sapiens ?
-
?
trypsinogen + H2O
-
Homo sapiens trypsin + ?
-
?
trypsinogen + H2O
-
Sus scrofa trypsin + ?
-
?
trypsinogen + H2O
-
Bos taurus trypsin + ?
-
?