Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | in vitro stimulation increases the mRNA levels of GZMB in both naive and memory cells. Activation-induced GZMB expression increases significantly faster and higher in memory cells than in naive cells for the first 24-32 h. At 72 h after stimulation, naive cells express higher levels of GZMB than do memory cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | induced hypoacetylation in GZMB gene loci by a HAT inhibitor (curcumin) results in decreased expressions of GZMB in memory cells in response to in vitro stimulation | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
additional information | low levels of GZMB mRNA and no detectable levels of granzyme B protein in resting naive or memory CD8 T cells | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
GzmB | - |
Homo sapiens |