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Literature summary for 3.4.21.79 extracted from
- Involvement of granzyme B and granulysin in the cytotoxic response in lichen planus (2008), J. Cutan. Pathol., 35, 630-634.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | granzyme B plays a role in the cytotoxic response in lichen planus. It is a probable target for future immunomodulator therapy | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | CD8+ T cell | Homo sapiens | - |
| skin | low levels of granzyme B mRNA within non-lesional skin, significant increase in granzyme B expression within lichen planus lesions. Positive correlation between levels of mRNA of granzyme B and granulysin within lesions of lichen planus | Homo sapiens | - |
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