Activating Compound | Comment | Organism | Structure |
---|---|---|---|
additional information | CMV/EBV/influenza peptide pool peptides do not induce GzB release in CD8+ cells from healthy donors within 24 h. Purified CD8+ cells after CMV/EBV/influenza peptide pool peptide stimulation show induction of GzB after 72 h in vitro. HIV peptides induce GzB secretion in HIV-infected individuals directly ex vivo | Homo sapiens |
Application | Comment | Organism |
---|---|---|
medicine | extension of the present standard of IFN-gamma measurements to the analysis of GzB and perforin release in functional T cell assays will provide new insights into CD8+ effector T cell function in HIV infection | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
HIV-positive patients and healthy controls | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
blood | - |
Homo sapiens | - |
additional information | CD8+ T cell | Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
GzB | - |
Homo sapiens |