Literature summary for 3.4.21.78 extracted from

Shacklett, B.L.; Cox, C.A.; Quigley, M.F.; Kreis, C.; Stollman, N.H.; Jacobson, M.A.; Andersson, J.; Sandberg, J.K.; Nixon, D.F.
Abundant expression of granzyme A, but not perforin, in granules of CD8+ T cells in GALT: implications for immune control of HIV-1 infection (2004), J. Immunol., 173, 641-648.

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Application

Application	Comment	Organism
medicine	granzyme A is located in intracellular granules of rectal CD8+ T cells in healthy and HIV-1-positive individuals, while similar amounts of perforin RNA are detected in both groups, but perforin protein is absent in rectal tissue of HIV-1-positive individuals	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasmic vesicle	intracellular granule	Homo sapiens	31410	-

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
T-lymphocyte	rectal CD8+ T cell	Homo sapiens	-

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Release 2023.1 (January 2023)