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BRENDA support

Literature summary for 3.4.21.77 extracted from

  • Jansen, F.H.; van Schaik, R.H.; Kurstjens, J.; Horninger, W.; Klocker, H.; Bektic, J.; Wildhagen, M.F.; Roobol, M.J.; Bangma, C.H.; Bartsch, G.
    Prostate-specific antigen (PSA) isoform p2PSA in combination with total PSA and free PSA improves diagnostic accuracy in prostate cancer detection (2010), Eur. Urol., 57, 921-927.
    View publication on PubMed

Application

Application Comment Organism
medicine evaluation of the use of PSA isoforms p2PSA and benign prostatic hyperplasia-associated PSA, BPHA, in prostate cancer predictive value. The p2PSA and Beckman Coulter Prostate Health Index levels differ significantly between men with and without prostate cancer. No difference in BPHA levels is observed. there are significant increases in prostate cancer predictive value and specificity of Beckman Coulter Prostate Health Index and percent free prostate-specific antigen compared to total prostate-specific antigen tPSA and percent free prostate-specific antigen. p2PSA has limited additional value in identifying aggressive prostate cancer Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
serum
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Homo sapiens
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