Literature summary for 3.4.21.77 extracted from

Stephan, C.; Cammann, H.; Deger, S.; Schrader, M.; Meyer, H.A.; Miller, K.; Lein, M.; Jung, K.
Benign prostatic hyperplasia-associated free prostate-specific antigen improves detection of prostate cancer in an artificial neural network (2009), Urology, 74, 873-877.

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Application

Application	Comment	Organism
medicine	although benign prostatic hyperplasia-associated as single marker or ratio to total PSA does not improve the diagnostic performance of percent free PSA or total PSA, the incorporation of benign prostatic hyperplasia-associated/total PSA into an artificial neural network model increases the specificity compared with percent free PSA by 13% and 17% at 90% and 95% sensitivity, respectively. Thus, automated benign prostatic hyperplasia-associated research assay may improve prostate cancer detection when incorporating this new marker into an artificial neural network	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
serum	white men with a total PSA concentration of 0-10 ng/mL, having prostate cancer or no evidence of malignancy, but in great part with benign prostatic hyperplasia	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
prostate-specific antigen	-	Homo sapiens
PSA	-	Homo sapiens

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Release 2023.1 (January 2023)