Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
22Rv1 cell | - |
Homo sapiens | - |
LNCaP cell | - |
Homo sapiens | - |
PC-3 cell | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
prostate specific antigen | - |
Homo sapiens |
PSA | - |
Homo sapiens |
Organism | Comment | Expression |
---|---|---|
Homo sapiens | shRNA mediated knockdown of SNF2-related CBP activator protein results in decreased H2A.Z binding at the enhancer region of the PSA promoter and decreased expression of PSA in prostate cancer cells | down |
Homo sapiens | SNF2-related CBP activator protein is a physiologically relevant mediator of PSA expression: it enhances the transcriptional activity of PSA and this activation is further enhanced in the presence of dihydrotestosterone. SNF2-related CBP activator protein activates hormone-dependent transcription of the androgen responsive, PSA-Luciferase reporter gene in prostate cells | up |