Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.77 extracted from

  • Karuppaiya, A.; Cheah, S.H.; Mohd, S.; Kamal, W.H.; Zulkifli, M.H.
    Generation and characterization of monoclonal antibodies against prostate-specific antigen (2009), Hybridoma, 28, 133-137.
    View publication on PubMed

Application

Application Comment Organism
medicine generation of stable hybridomas producing specific monoclonal antibodies of the IgG class against PSA from fusions of splenocytes from immunized mice with myeloma cells, which can be used to develop radioimmunodiagnostic, radioimaging, and immunohistochemistry techniques for the early detection and treatment of prostate cancer Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
LNCaP cell
-
Homo sapiens
-

Synonyms

Synonyms Comment Organism
prostate-specific antigen
-
Homo sapiens
PSA
-
Homo sapiens

General Information

General Information Comment Organism
physiological function 125I-labeled specific monoclonal antibodies demonstrate strong binding to PSA on the surface of LNCaP cells Homo sapiens