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Literature summary for 3.4.21.77 extracted from
- Interplay of human tissue kallikrein 4 (hK4) with the plasminogen activation system: hK4 regulates the structure and functions of the urokinase-type plasminogen activator receptor (uPAR) (2006), Biol. Chem., 387, 217-222.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | enzyme may modulate the tumor-associated urokinase-type plasminogen activator/urokinase-type plasminogen activator receptor-system activity by either activating the pro-enzyme form of plasminogen activator or cleaving the cell surface-associated receptor | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
isoform tissue kallikrein 4, hK4 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| urokinase-type plasminogen activator receptor + H2O | - |
Homo sapiens | ? | cleavage within D1-D2 linker sequence and in its D3 juxtamembrane domain | ? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| K4 | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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