Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.77 extracted from

  • Watt, K.W.K.; Lee, P.J.; M`Timkulu, T.; Chan, W.P.; Loor, R.
    Human prostate-specific antigen: structural and functional similarity with serine proteases (1986), Proc. Natl. Acad. Sci. USA, 83, 3166-3170.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 3.4.21.77

Inhibitors

Inhibitors Comment Organism Structure
Aprotinin
-
 Homo sapiens
diisopropylfluorophosphate
-
 Homo sapiens
L-1-tosylamido-2-phenylethyl chloromethyl ketone
-
 Homo sapiens
leupeptin
-
 Homo sapiens
PMSF
-
 Homo sapiens
Soybean trypsin inhibitor
-
 Homo sapiens
spermidine
-
 Homo sapiens
Zn2+
-
 Homo sapiens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
15.3
-
 N-succinyl-L-Ala-L-Ala-L-Pro-L-Phe 4-nitroanilide
-
 Homo sapiens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
26500
-
 calculation from amino acid sequence Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein an N-linked carbohydrate side chain is predicted at Asp45, and O-linked carbohydrate side chains are possibly attached to Ser69, Thr70 and Ser71 Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
seminal plasma
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
N-alpha-benzoyl-DL-Arg 4-nitroanilide + H2O trypsin-like activity Homo sapiens N-alpha-benzoyl-DL-Arg + 4-nitroaniline
-
 ?
N-succinyl-L-Ala-L-Ala-L-Pro-L-Phe 4-nitroanilide + H2O chymotrypsin-like activity Homo sapiens N-succinyl-L-Ala-L-Ala-L-Pro-L-Phe + 4-nitroaniline
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.075
-
 N-succinyl-L-Ala-L-Ala-L-Pro-L-Phe 4-nitroanilide
-
 Homo sapiens