Literature summary for 3.4.21.76 extracted from

Damoiseaux, J.; Daehnrich, C.; Rosemann, A.; Probst, C.; Komorowski, L.; Stegeman, C.A.; Egerer, K.; Hiepe, F.; van Paassen, P.; Stoecker, W.; Schlumberger, W.; Tervaert, J.W.
A novel enzyme-linked immunosorbent assay using a mixture of human native and recombinant proteinase-3 significantly improves the diagnostic potential for antineutrophil cytoplasmic antibody-associated vasculitis (2009), Ann. Rheum. Dis., 68, 228-233.

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Application

Application	Comment	Organism
medicine	novel anti-proteinase-3-human native-human recombinant enzyme-linked immunosorbent assay (ELISA) with a very high sensitivity for the detection of proteinase-3-antineutrophil cytoplasmic antibodies (ANCA) in patients with ANCA-associated vasculitis with C-ANCA	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
DELTAAE-PR3(S176A)-His expressed in HEK-293 cells	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
S176A	substitution of the active centre	Homo sapiens

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	P24158	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
granulocyte	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
PR3	-	Homo sapiens
Proteinase-3	-	Homo sapiens

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Release 2023.1 (January 2023)