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Literature summary for 3.4.21.75 extracted from
- Development and characterisation of an assay for furin activity (2011), J. Immunol. Methods, 364, 101-108.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | sensitive and specific assay for furin activity using an antibody capture step to immobilise furin from whole cell lysates. The assay has a minimum detection limit of 0.006 nM and is sensitive enough to determine the furin activity of many of the cell lines tested | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Hep-G2 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| pGlu-Arg-Thr-Lys-4-methylcoumarin 7-amide + H2O | - |
Homo sapiens | pGlu-Arg-Thr-Lys + 7-amino-4-methylcoumarin | - |
? |  |
Expression
| Organism | Comment | Expression |
|---|---|---|
| Homo sapiens | cytokine transforming growth factor TGF-beta stimulates furin mRNA expression in HepG2 cells | up |
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