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Literature summary for 3.4.21.75 extracted from
- Effect of ultraviolet radiation on the expression of pp38MAPK and furin in human keratinocyte-derived cell lines (2009), Photodermatol. Photoimmunol. Photomed., 25, 20-29.
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| additional information | expression of furin in irradiated Colo-16 cells remains constant for 48 h following exposure of the cells to either low dose UVA and/or UVB radiation, and high-dose UVA radiation. In cells irradiated with high-dose UVB radiation, significant increase in furin expression commencing at 12 h, which peaks at 24 h (5fold). Correlation between expression of pp38 and furin in Colo-16 cells, but not HaCaT cells, following UV exposure | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | expression of furin in HaCaT cells declines with respect to time in response to UV radiation irrespective of the type or the dose used | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| HaCaT cell | - |
Homo sapiens | - |
| keratinocyte | - |
Homo sapiens | - |
| additional information | Colo-16 cell | Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Proprotein convertase | - |
Homo sapiens |
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