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Literature summary for 3.4.21.75 extracted from

  • Koo, B.H.; Longpre, J.M.; Somerville, R.P.; Alexander, J.P.; Leduc, R.; Apte, S.S.
    Cell-surface processing of pro-ADAMTS9 by furin (2006), J. Biol. Chem., 281, 12485-12494.
    View publication on PubMed
Search for more literature for 3.4.21.75

Localization

Localization Comment Organism GeneOntology No. Textmining
cell surface
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 Homo sapiens 9986
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
ADAMTS9 propeptide + H2O Homo sapiens the intact zymogen is secreted to the cell surface and is subsequently processed by furin before release into thge medium. ADAMTS9 processing is exclusively extracellular and occurs at the cell surface in cells that express high levels of furin ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
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Source Tissue

Source Tissue Comment Organism Textmining
HEK-293F cell
-
 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ADAMTS9 propeptide + H2O the intact zymogen is secreted to the cell surface and is subsequently processed by furin before release into thge medium. ADAMTS9 processing is exclusively extracellular and occurs at the cell surface in cells that express high levels of furin Homo sapiens ?
-
 ?
ADAMTS9 propeptide + H2O ADAMTS is a disintegrin and metalloprotease domain with thrombospondin type 1 repeats Homo sapiens ?
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 ?