Literature summary for 3.4.21.75 extracted from

Peinado, J.R.; Kacprzak, M.M.; Leppla, S.H.; Lindberg, I.
Cross-inhibition between furin and lethal factor inhibitors (2004), Biochem. Biophys. Res. Commun., 321, 601-605.

Search for more literature for 3.4.21.75

Inhibitors

Inhibitors	Comment	Organism	Structure
(D-Arg)6 amide	IC50: 0.3 mM	Mus musculus
(D-Arg)9 amide	IC50: 0.01 mM	Mus musculus
lethal factor inhibitor 2	IC50: 0.002 mM	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
lethal factor inhibitor 2 + H2O	-	Mus musculus	?	-	?
pGlu-Arg-Thr-Lys-Arg-4-methylcoumaryl-7-amide + H2O	-	Mus musculus	?	-	?

IC50 Value

IC50 Value	IC50 Value Maximum	Comment	Organism	Inhibitor	Structure
0.002	-	IC50: 0.002 mM	Mus musculus	lethal factor inhibitor 2
0.01	-	IC50: 0.01 mM	Mus musculus	(D-Arg)9 amide
0.3	-	IC50: 0.3 mM	Mus musculus	(D-Arg)6 amide

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Release 2023.1 (January 2023)