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Literature summary for 3.4.21.75 extracted from
- The furin inhibitor hexa-D-arginine blocks the activation of Pseudomonas aeruginosa exotoxin A in vivo (2002), Infect. Immun., 70, 7136-7139.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| soluble ectodomain of furin is expressed in dihydrofolate reductase-amplified CHO cells | Mus musculus |
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| triclinic crystals, space group P1, unit cell dimensions a = 93.3 A, b = 135.4 A, c = 137.8 A | Mus musculus |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| decanoyl-Arg-Val-Lys-Arg-chloromethylketone | - |
Mus musculus |  |
| hexa-D-arginine | - |
Mus musculus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
mouse | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Pseudomonas aeruginosa exotoxin A + H2O | - |
Mus musculus | ? | - |
? | |
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