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Literature summary for 3.4.21.73 extracted from

  • Naruse, K.; Lash, G.E.; Bulmer, J.N.; Innes, B.A.; Otun, H.A.; Searle, R.F.; Robson, S.C.
    The urokinase plasminogen activator (uPA) system in uterine natural killer cells in the placental bed during early pregnancy (2009), Placenta, 30, 398-404.
    View publication on PubMed
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Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens uterine natural killer cells may regulate extravillous trophoblast invasion and spiral artery remodeling via the uPA system ?
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Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining
natural killer cell uPA localizes strongly to natural killer cells of the placental bed, especially at 8-10 weeks of gestation. uPA activity is similar in uterine natural killer cell culture supernatant compared with total unseparated decidual cells. uPA receptor in uterine natural killer cell lysates is significantly stronger than in total decidual cell lysates. Inhibitors PAI-1 and PAI-2 are not detected in uterine natural killer cell culture supernatants Homo sapiens
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placenta uPA localizes strongly to natural killer cells of the placental bed, especially at 8-10 weeks of gestation. uPA activity is similar in uterine natural killer cell culture supernatant compared with total unseparated decidual cells. uPA receptor in uterine natural killer cell lysates is significantly stronger than in total decidual cell lysates. Inhibitors PAI-1 and PAI-2 are not detected in uterine natural killer cell culture supernatants Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information uterine natural killer cells may regulate extravillous trophoblast invasion and spiral artery remodeling via the uPA system Homo sapiens ?
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 ?