Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.73 extracted from

  • Van Den Broeck, T.; Stevenaert, F.; Taveirne, S.; Debacker, V.; Vangestel, C.; Vandekerckhove, B.; Taghon, T.; Matthys, P.; Plum, J.; Held, W.; Dewerchin, M.; Yokoyama, W.M.; Leclercq, G.
    Ly49E-dependent inhibition of natural killer cells by urokinase plasminogen activator (2008), Blood, 112, 5046-5051.
    View publication on PubMed

Application

Application Comment Organism
medicine possible involvement of uPA in natural killer cell-mediated immune surveillance and tumor escape. Addition of uPA to natural killer cell receptor Ly49E positive adult and fetal natural killer cells inhibits interferon-gamma secretion and reduces their cytotoxic potential, respectively Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus addition of uPA to natural killer cell receptor Ly49E positive adult and fetal natural killer cells inhibits interferon-gamma secretion and reduces their cytotoxic potential, respectively. Effects are dependent on receptor Ly49E ?
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information addition of uPA to natural killer cell receptor Ly49E positive adult and fetal natural killer cells inhibits interferon-gamma secretion and reduces their cytotoxic potential, respectively. Effects are dependent on receptor Ly49E Mus musculus ?
-
?