Literature summary for 3.4.21.73 extracted from

Kim, C.K.; Hong, S.H.; Joe, Y.A.; Shim, B.S.; Lee, S.K.; Hong, Y.K.
The recombinant kringle domain of urokinase plasminogen activator inhibits in vivo malignant glioma growth (2007), Cancer Sci., 98, 253-258.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression of the enzyme's kringle domain UK1 in Pichia pastoris	Homo sapiens

Protein Variants

Protein Variants	Comment	Organism
additional information	the isolated recombinant kringle domain UK1 of uPA shows in vivo antitumor effects in a brain tumor model, systemic administration of purified recombinant UK1 leads to suppression of the growth of a U87 human glioma xenograft, implanted into the brains of male BALB/cSlc nude mice, overview	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
recombinant isolated kringle domain UK1 from Pichia pastoris	Homo sapiens

Synonyms

Synonyms	Comment	Organism
uPA	-	Homo sapiens
Urokinase plasminogen activator	-	Homo sapiens

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Release 2023.1 (January 2023)