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Literature summary for 3.4.21.73 extracted from

  • Lijnen, H.R.; van Hoef, B.; Nelles, L.; Collen, D.
    Plasminogen activation with single-chain urokinase-type plasminogen activator (scu-PA). Studies with active site mutagenized plasminogen (Ser740----Ala) and plasmin-resistant scu-PA (Lys158----Glu) (1990), J. Biol. Chem., 265, 5232-5236.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
recombinant plasmin-resistant mutant of single-chain uPA obtained by site-specific mutagenesis of Lys158 to Glu
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
plasminogen + H2O
-
Homo sapiens plasmin + ?
-
?