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Literature summary for 3.4.21.7 extracted from

  • Robbins, K.; Summaria, L.; Wohl, R.C.
    Human plasmin (1981), Methods Enzymol., 80, 379-387.
    View publication on PubMed
Search for more literature for 3.4.21.7

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0135
-
 benzyloxycarbonyl-Lys-p-nitrophenyl ester Glu1-plasminogen Homo sapiens
0.015
-
 benzyloxycarbonyl-Lys-p-nitrophenyl ester Lys77-plasminogen Homo sapiens
0.083
-
 benzyloxycarbonyl-Lys-p-nitrophenyl ester Val561-plasminogen Homo sapiens
0.21
-
 D-Val-Leu-Lys-p-nitroanilide Lys77-plasmin Homo sapiens
0.28
-
 D-Val-Leu-Lys-p-nitroanilide Val442-plasmin Homo sapiens
1.26
-
 D-Val-Leu-Lys-p-nitroanilide Val561-plasmin Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
 various forms of enzyme: Glu1-plasmin, Lys77-plasmin, Val442-plasmin, Val561-plasmin
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
benzyloxycarbonyl-Lys-p-nitrophenyl ester + H2O
-
 Homo sapiens ?
-
 ?
D-Val-Leu-Lys-p-nitroanilide + H2O
-
 Homo sapiens D-Val-Leu-Lys + p-nitroaniline
-
 ?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.1
-
 benzyloxycarbonyl-Lys-p-nitrophenyl ester Val561-plasminogen Homo sapiens
14.5
-
 D-Val-Leu-Lys-p-nitroanilide Val561-plasmin Homo sapiens
22.3
-
 benzyloxycarbonyl-Lys-p-nitrophenyl ester Glu1-plasminogen and Lys77-plasminogen Homo sapiens
25.5
-
 D-Val-Leu-Lys-p-nitroanilide Val442-plasmin Homo sapiens
25.7
-
 D-Val-Leu-Lys-p-nitroanilide Lys77-plasmin Homo sapiens