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Literature summary for 3.4.21.7 extracted from

  • Foley, J.H.; Peterson, E.A.; Lei, V.; Wan, L.W.; Krisinger, M.J.; Conway, E.M.
    Interplay between fibrinolysis and complement: plasmin cleavage of iC3b modulates immune responses (2015), J. Thromb. Haemost., 13, 610-618.
    View publication on PubMed
Search for more literature for 3.4.21.7

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
inactive complement component C3b + H2O Homo sapiens plasmin degrades inactive complement component C3b through cleavage at R945 generating C3dg- and C3c-like species ?
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
blood
-
 Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
inactive complement component C3b + H2O plasmin degrades inactive complement component C3b through cleavage at R945 generating C3dg- and C3c-like species Homo sapiens ?
-
 ?

General Information

General Information Comment Organism
physiological function plasmin cleavage of inactive complement component C3b regulates macrophage interleukin-12 secretion Homo sapiens