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Literature summary for 3.4.21.7 extracted from
- Breast cyst fluid plasmin activity and its effect on TGF-beta2 activation (2008), Cancer Invest., 26, 22-27.
Application
| Application | Comment | Organism |
|---|---|---|
| medicine | plasmin activates transforming growth factor beta 2, which has a potential protective role in breast cancer by its inhibitory effect on epithelial cell growth | Homo sapiens |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alpha-antitrypsin | - |
Homo sapiens | |
| alpha2-antiplasmin | - |
Homo sapiens | |
| streptokinase | - |
Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| additional information | high level of plasmin activity in high electrolyte ratio breast cysts, which have a low risk for cancer development | Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| transforming growth factor beta 2 + H2O | - |
Homo sapiens | ? | - |
? |  |
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