Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 3.4.21.7 extracted from

  • Quagraine, M.O.; Tan, F.; Tamei, H.; Erdoes, E.G.; Skidgel, R.A.
    Plasmin alters the activity and quaternary structure of human plasma carboxypeptidase N (2005), Biochem. J., 388, 81-91.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
carboxypeptidase N + H2O plasmin cleaves the 83 kDa subunit of carboxypeptidase N between Arg457 and Ser458 and after prolonged incubation between Arg218 and Arg219. The small 55 kDa is cleaved to a 48 kDa product. The cleavage enhances the activity of carboxypeptidase N to 150% of the uncleaved enzyme Homo sapiens ?
-
?

Synonyms

Synonyms Comment Organism
plasmin
-
Homo sapiens