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Literature summary for 3.4.21.68 extracted from

  • Wilczak, N.; Elting, J.W.; Chesik, D.; Kema, I.P.; De Keyser, J.
    Intravenous tissue plasminogen activator in patients with stroke increases the bioavailability of insulin-like growth factor-1 (2006), Stroke, 37, 2368-2371.
    View publication on PubMed

Application

Application Comment Organism
medicine effects of intravenous administration of tPA on serum levels of IGF-1 and IGF-binding protein-3 in patients with acute ischemic stroke are investigated by radioimmunoassay in 10 patients. During tPA treatment, total IGF-1 and IGFBP-3 serum levels do not change, but there was an 70% increase in free IGF-1 serum levels at the end of the 1-h infusion. Intravenous therapy with tPA enhances the bioavailability of IGF-1 Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Synonyms

Synonyms Comment Organism
tPA
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Homo sapiens